• While lowering the TID exposure

  2020-05-08

  

  While lowering the TID exposure of electronics is fairly straightforward, there are other DOI hydrochloride induced effects that are not as easily mitigated, especially with COTS components. Single Event Effects (SEE) occur when a high-energy particle strikes the active area of an integrated circui

• Renal injury by cisplatin has

  2020-05-08

  

  Renal injury by cisplatin has been associated with oxidative stress, inflammation, and apoptosis (Francescato et al., 2007, Iseri et al., 2007, Kiymaz et al., 2008, Ueki et al., 2012). Specifically, apoptosis is an important mode of cell death in cisplatin nephrotoxicity, and many studies including

• Direct coupling between DNA methyltransferase

  2020-05-07

  

  Direct coupling between DNA methyltransferase enzymes and posttranslational modifications on histone proteins has been observed in mammals. For example, DNMT3A recognizes unmodified H3 through an ATRX-DNMT3-DNMT3L (ADD) domain, and its activity is inhibited by methylation of H3 at K4 (Li et al., 201

• Since anti MMP Therapy anti iNOS therapy TNF and

  2020-05-07

  

  Since, anti-MMP Therapy [9], anti-iNOS therapy [10], TNF-α and IL-1β inhibitor (Diacerhein) [11] etc. are some of the disease modifying anti-osteoarthritis drugs have been used. But their action based on the evidence from the clinical trial and scientific literature suggesting the therapeutic effica

• br Experimental section br Results

  2020-05-07

  

  Experimental section Results Discussion In our previous work (Rashidi et al., 2018) we isolated a novel glucarpidase whose raised Necrosulfonamide did not cross-react with the one in clinical use. In principle, therefore, it would be possible to delay the production of antibodies in a pati

• br User knowledge representation Various representation appr

  2020-05-07

  

  User knowledge representation Various representation approaches of user interests and preferences are proposed. In this work, we advocate a multidimensional semantic approach based on Bouzghoub et al. meta-model (Bouzeghoub and Kostadinov, 2005), depicted in Fig. 6, to model the user profile. The

• Studies have shown that endothelial cells

  2020-05-06

  

  Studies have shown that endothelial cells damaged by SAH can release a large amount of ET-1, thus its plasma level is elevated and is positively correlated with the symptoms of SAH (Lei et al., 2015, Masaoka et al., 1989). Our data obtained from SAH-along rabbits were consistent with these findings

• Sodium valproate br GPCRs form heterotetramers In addition t

  2020-05-06

  

  GPCRs form heterotetramers In addition to homodimers and heterodimers, for several family A receptor heteromers, experimental evidence supports the presence of higher order rearrangements as tetrameric structures, comprised of two different homodimers, each able to signal with its preferred G pro

• In our recent study we established

  2020-05-06

  

  In our recent study, we established a procedure to examine the chromatin binding of XRCC4 using a biochemical fractionation analysis using a detergent Nonidet P-40 [22]. In this study, we investigated the role of LIG4 and its subdomains in the recruitment of XRCC4/LIG4 complex to chromatin. Mater

• br Acknowledgements br Introduction Water and electrolytes c

  2020-05-06

  

  Acknowledgements Introduction Water and electrolytes constitute an integral part of all living things, and hydrazide governing their movements play important roles in a wide variety of physiological and/or pathophysiological processes. Given the importance of channel proteins in cancer cell p

• The pyrrolo benzodiazepines PBDs are

  2020-05-06

  

  The pyrrolo[2,1-][1,4]benzodiazepines (PBDs) are a family of antitumour antibiotics that includes the natural products anthramycin and DC-81. They exert their cytotoxicity by covalently bonding to the exocyclic C2–NH group of guanine residues in the minor groove of DNA through their N10–C11 imine fu

• br Discussion Variable estradiol effects on

  2020-05-06

  

  Discussion Variable estradiol effects on cell proliferation have been reported according to animal species, tissues, and type of estrogen receptor [16,21,22,[29], [30], [31]]. In the kidney, 17βE was found to increase [3H]-thymidine incorporation in primary rabbit kidney proximal tubule Carprofen

• aminoisobutyric acid BAIBA is a natural catabolite

  2020-05-06

  

  β-aminoisobutyric Flavin adenine dinucleotide mg (BAIBA) is a natural catabolite of the branched-chain amino acid thymine. BAIBA was recently found to reduce inflammation in skeletal muscle via the AMP-activated protein kinase (AMPK)-peroxisome proliferator-activated receptor (PPAR)δ signaling path

• br Results and Discussion br Conclusions Understanding the c

  2020-05-06

  

  Results and Discussion Conclusions Understanding the connections between function and fitness is a primary goal of many biological disciplines including systems biology and molecular evolution. While sound approaches have been developed to understand the connections between function and fitnes

• Dopamine activity in the PFC and striatum may

  2020-05-05

  

  Dopamine activity in the PFC and striatum may be antagonistic, meaning that lower levels of dopamine in the striatum tend to correspond to higher levels of dopamine in the PFC and vice versa (Cools and D\'Esposito, 2011; Tunbridge et al., 2006). Human PET studies have reported that dopaminergic PFC

14847 records 834/990 page Previous Next First page 上5页 831832833834835 下5页 Last page