• Municipal WAS waste activated sludge contains

  2020-08-06

  

  Municipal WAS (waste activated sludge) contains predominant organic contaminants namely proteins, polysaccharides, lipids etc, which must be hydrolysed to simple units by extracellular enzymes which are revealed by consortium of microbial species [8], [9]. Microbes and WAS activity were measured bas

• Enzyme mimics belong to a type of

  2020-08-06

  

  Enzyme mimics belong to a type of rising catalysts which show the similar function with their corresponding natural enzymes [20], [21], [22], [23], [24], [25], [26], [27], although their structures are different from natural enzymes. In the area of prodrug activation, the widely-used enzyme mimics a

• It is without doubt that the vagina plays

  2020-08-05

  

  It is without doubt that the vagina plays a significant role in the perception of coital stimulation leading to sexual arousal and, finally, orgasm. In response to sensory stimulation, relaxation of vaginal vascular and nonvascular smooth muscle occurs, resulting in an increase in local blood flow a

• In anaphase APC CCDC recruits substrates while the

  2020-08-05

  

  In anaphase, APC/CCDC20 recruits substrates, while the APC2–APC11 cullin–RING catalytic core engages, positions, and activates transient E2∼Ub intermediates (e.g., UBE2C∼Ub, where ‘∼’ refers to thioester bond) from which Ub is transferred to a coactivator-bound substrate (Figure 2B, Conformation VI)

• br Materials and methods br Results br Discussion

  2020-08-05

  

  Materials and methods Results Discussion In contrast to our observations of DNA-PK-dependent H2AX phosphorylation during apoptosis, we have previously shown that ATM is primarily responsible for γH2AX induction in murine YM201636 in response to IR [41]. However, other reports have implicat

• Herein the SNP and INDEL variant effect prediction

  2020-08-05

  

  Herein, the SNP and INDEL variant effect prediction data presented by Wendt et al. [27] are expanded upon using the phased data of the 1000 Genomes Project [28]. Full-gene haplotypes of UGT2B7, ABCB1, OPRM1, and COMT were characterized in self-reported healthy individuals. When compared to CYP2D6-pr

• The atherosclerotic vascular occlusive diseases risk of OC i

  2020-08-05

  

  The atherosclerotic vascular occlusive diseases risk of OC is partly attributed to their adverse effects on lipid and blue nitro sale metabolism [18]. It has been demonstrated that impaired fasting blood glucose, impaired glucose tolerance and unfavourable lipid profile are important risk factors fo

• Uniform clusters of calcium silicate hydrates

  2020-08-05

  

  Uniform clusters of calcium-silicate-hydrates (C-S-H) are formed through the chemical pozzolanic reactions between the calcium hydroxide produced by the cement hydration and amorphous silica of RHA that result in a higher densification of the matrix [12]. The addition of well pulverized RHA to cemen

• Adox br The regulation of DNA PK activity

  2020-08-04

  

  The regulation of DNA-PK activity How DNA-PK is activated or deactivated in response to DNA damage and other cellular stress, is still relatively unknown [38]. Previous studies have shown that two serine/threonine protein phosphatase PP5 and PP6 are involved in DNA-PK activity modulation [39], [4

• Collagen alignment can contribute to tissue stiffening Malik

  2020-08-04

  

  Collagen alignment can contribute to tissue stiffening (Malik et al., 2015, Paszek et al., 2005), and ECM stiffness in turn is a powerful activator of integrin function (Levental et al., 2009). These findings highlight the contribution of the mechanical properties of the ECM to signal transduction.

• Direct use of the fermentation broth at

  2020-08-04

  

  Direct use of the fermentation broth at the end of fermentation process in the subsequent biotransformation process could be achieved by supplementing 1L of broth with 0.881g ascorbic acid, 0.278g FeSO4·7H2O, 17.1g α-ketoglutarate, 20mL of 1M potassium phosphate buffer and 10g of l-proline. The biot

• br Introduction A pretreatment technique named porous membra

  2020-08-04

  

  Introduction A pretreatment technique named porous membrane protected micro-solid-phase extraction (μ-SPE) was proposed by Basheer et al. in 2006 [1]. It is based on the packing of small amount of sorbent material in a sealed porous membrane envelope. Compared to other pretreatment techniques, th

• The Egr gene is one of the

  2020-08-04

  

  The Egr1 gene is one of the early response genes dramatically and rapidly induced upon stimulation with many environmental signals including growth factors, hormones, and neurotransmitters (Gupta et al., 1991, Kaufmann et al., 2001, Liu et al., 2005, Sato et al., 1999). Egr1 functions as a convergen

• br Results and discussion br

  2020-08-04

  

  Results and discussion Conclusion Analogues of benzothiazole have been synthesized and characterized. To avoid late stage failure, it is important to study the preliminary pharmacokinetic parameters. The results of in silico pharmacokinetic data suggested that all the molecules might be consid

• At present there have been no studies on the

  2020-08-03

  

  At present, there have been no studies on the relationship between CYP2D6 gene polymorphism and the lipid-lowering effect of atorvastatin. Our results showed that the rs1065852 in CYP2D6 influences the effectiveness of atorvastatin, and the GG genotype had a better response to atorvastatin therapy,

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