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br Conclusion br Acknowledgments br
2022-02-17

Conclusion Acknowledgments Introduction Throughout history, there is literature that supports the notion that animals can be perceived as “healing”. Overall, there is an increased interest in the general field of Animal Assisted Therapy (AAT). Though the field of equine-facilitated psychoth
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Phylogenetic analysis of the secretin like
2022-02-17

Phylogenetic analysis of the secretin-like hormones yields poorly supported trees due to the short length of their peptide sequences (Dores et al., 1996). However, phylogenetic analyses typically show that the secretin-like peptides encoded by the proglucagon (glucagon, GLP-1 and GLP-2) and GIP cmk
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Considerable evidence links sustained GCG administration to
2022-02-17

Considerable evidence links sustained GCG administration to the reduction of food intake, enhancement of energy expenditure and weight loss in rodent and human studies [16], [17], [18]. Moreover, patients presenting with GCG-producing tumors frequently manifest severe weight loss, through mechanisms
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br Voltage dependent anion channel VDAC is
2022-02-17

Voltage-dependent anion channel VDAC is a ubiquitous protein showing well conserved structural and functional properties in spite of major variations in its sequence (for review see [50]). Most of what we know about VDAC electrophysiological properties (for reviews, see [51], [52]) was initially
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Introduction Osteoclasts are large multinuclear cells that a
2022-02-16

Introduction Osteoclasts are large, multinuclear get more information that are responsible for the resorption (breakdown) of bone [1]. Together with osteoblasts, the bone forming cell, they maintain the integrity of the skeleton through constant resorption and repair of bone. Osteoclast precursors
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Polyunsaturated fatty acids PUFAs represent a class of
2022-02-16

Polyunsaturated fatty acids (PUFAs) represent a class of lipids that contain two or more carbon double (unsaturated) bonds (CC) and classified as n-3, n-6 and n-9 fatty acids. PUFAs including n-3 such as docosahexaenoic gmol (DHA), eicosapentaenoic acid (EPA) and n-6 such as arachidonic acid (AA) a
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renin inhibitor We used a culture model of human erythropoie
2022-02-16

We used a culture model of human erythropoiesis that recapitulates all developmental stages [24] to screen a focused set of lncRNAs for potential contribution to this program. We found induction of lncRNA Fas-antisense 1 (Fas-AS1 or Saf) during RBC maturation and demonstrate that essential erythroid
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One PKC target that controls cortical actin structure is
2022-02-16

One PKC target that controls cortical chemokine receptor structure is a well-known actin crosslinking protein, myristoylated alanine-rich C-kinase substrate (MARCKS). MARCKS cross-links actin and binds PIP2 and this binding activity is regulated by PKC phosphorylation [82]. Activation of PKC releas
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br STAR Methods br Acknowledgments We thank
2022-02-16

STAR★Methods Acknowledgments We thank Emeritus Professor Chikashi Shimoda and Professor Taro Nakamura of the National BioResource Project/Yeast Genetic Resource Center (NBRP/YGRC) at Osaka City University (Osaka, Japan) for Schizosaccharomyces pombe meiotic cDNA library, yeast plasmids, yeast
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The neurotransmitter histamine plays a
2022-02-16

The neurotransmitter histamine plays a key role in the sleep-wake cycle and in learning and memory. Alterations in MK0752 histamine levels are closely connected with central nervous system dysfunction, and are thought to contribute to neurological disorders, including Alzheimer's disease and depres
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Despite these studies little is known
2022-02-16

Despite these studies, little is known about the regulation of defence genes during AM root colonization. In the present study, we characterized the Ptc52 gene from tomato (named here as SlPtc52), a member of the gene family of non-heme oxygenases, and analysed its molecular characteristics. This ge
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Biological evaluations of the compounds
2022-02-16

Biological evaluations of the compounds were done both using HCV protease and replicon assays. Results are shown in . The protease inhibitory IC’s were determined using a FRET assay with HCV NS3/4A 1a protease domain. The replicon EC’s were determined using a replicon luciferase cell-based assay. Th
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br Conclusions br Introduction Astrocytes contribute to
2022-02-16

Conclusions Introduction Astrocytes contribute to physiological Meropenem trihydrate function on many levels. They help maintain the physiological composition of the extracellular medium by, for instance, buffering potassium and uptake of neurotransmitters. They can also provide neurons with e
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3934 Over the last few years experimental
2022-02-15

Over the last few years, experimental evidence for the involvement of Epac1 in cancer progression is beginning to emerge (Almahariq et al., 2015, Banerjee and Cheng, 2015, Parnell et al., 2015, Parnell et al., 2015, Schmidt et al., 2013). For example in melanoma cells, silencing of Epac1 attenuates
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It has been suggested that
2022-02-15

It has been suggested that the presence of nutrient-sensing receptors and their natural ligands originating from different metabolic pathways in farm animals, are related to the critical outcome of metabolic-derived diseases in cattle (Mielenz, 2017). Thus, current article aimed to review the most r
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